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Understanding Pouchitis
Pouchitis is a complication that may occur after having J-pouch surgery. It’s when a pouch made during the surgery becomes red and swollen (inflamed).
J-pouch surgery helps treat conditions like Crohn’s disease and ulcerative colitis. During this procedure, a person’s colon and rectum are removed. A surgeon then replaces the rectum with a manmade pouch. The surgeon makes the pouch from the ileum. The ileum is the last part of the small intestine.
The pouch is shaped like the letter J. It works like the rectum. It holds waste until it leaves the body through the anus. After the surgery, the lining of the pouch may become inflamed. This is pouchitis.
What causes pouchitis?
Experts aren’t quite sure what causes pouchitis. But after J-pouch surgery, bacteria that live in the gut change. The immune system may react to this change. This may cause the inflammation.
You may be at a higher risk of getting pouchitis after J-pouch surgery if you:
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Have ulcerative colitis.
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Have chronic liver disease.
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Have a viral or bacterial infection.
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Smoke.
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Take nonsteroidal anti-inflammatory drugs (NSAIDs).
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Are male.
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Have had belly surgery in the past.
Symptoms of pouchitis
Symptoms of pouchitis include:
To find out if you have pouchitis, your doctor will ask about your symptoms. You may also need these tests:
Treatment for pouchitis
The main treatment for pouchitis is antibiotics. You will take this medicine for a few weeks. If your symptoms don’t go away or they come back, your doctor may try other antibiotics or different medicines.
If your doctor prescribed antibiotics, take them as directed. Do not stop taking them just because you feel better. You need to take the full course of antibiotics.
If pouchitis lasts for more than 4 weeks, you may have to keep taking the antibiotics or different medicines to control your symptoms. Your doctor may also advise that you:
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Stop taking NSAIDs such as ibuprofen because these can make pouchitis worse.
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Stop smoking. This can make pouchitis worse.
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Have surgery to fix any problems that may be causing pouchitis.
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Treat other possible causes of pouchitis, such as an infection.
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Take other medicines as prescribed. Discuss any over-the-counter medicines or probiotics with your doctor before taking them.
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Make some life changes. Losing weight may help. So, too, may eating foods low in carbohydrates or fiber.
When to contact your doctor
Contact your doctor right away if:
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You have a fever of 100.4°F (38°C) or higher, or as directed by your doctor.
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You have belly (abdominal) pain.
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Your pain gets worse.
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You have rectal bleeding.
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Your symptoms don’t get better, or they get worse.
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You have new symptoms.
Online Medical Reviewer:
L Renee Watson MSN RN
Online Medical Reviewer:
Robyn Zercher FNP
Date Last Reviewed:
6/1/2025
© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.